Rejuran Injections

Clinicbe in Knightsbridge London now offers the latest advanced Rejuran injections as part of our regenerative skin treatment portfolio designed to repair, restore and improve overall skin quality at a cellular level.

Rejuran is a polynucleotide (PN) skin rejuvenation treatment derived from DNA fragments that work to support natural skin healing, improve elasticity and strengthen the skin barrier for healthier, more resilient skin over time.

What is Rejuran?

Rejuran is an injectable skin rejuvenation treatment containing polynucleotides (PN), bioactive molecules derived from salmon DNA that are highly biocompatible with human skin.

It is designed to improve skin quality rather than add volume, making it fundamentally different from dermal fillers.

Rejuran works by supporting skin repair mechanisms, improving cellular regeneration, strengthening the dermal structure and enhancing overall skin health, texture and hydration.

It is particularly effective for improving delicate or damaged skin that requires repair rather than volumisation.

How Rejuran Works

Rejuran works at a cellular level to support skin healing and regeneration.

Once injected into the skin, polynucleotides stimulate fibroblast activity, enhance microcirculation and support the production of collagen and extracellular matrix components.

This leads to progressive improvements in:

  • Skin repair and regeneration
  • Elasticity and firmness
  • Hydration and barrier function
  • Skin texture and smoothness
  • Overall skin resilience

Unlike treatments that provide immediate structural change, Rejuran works gradually by improving the skin’s internal quality and function over time.

Benefits of Rejuran Injections

  • Supports natural skin repair and regeneration
  • Improves overall skin texture and smoothness
  • Strengthens skin barrier function
  • Enhances hydration and elasticity
  • Reduces appearance of fine lines and crepey skin
  • Improves skin quality in delicate areas
  • Promotes healthier, more resilient skin
  • Suitable for sensitive or damaged skin types

Treatment Areas

Rejuran is commonly used to treat delicate and ageing skin in areas such as:

  • Under-eyes (tear trough area)
  • Cheeks
  • Full face
  • Neck
  • Décolletage

Treatment is tailored depending on skin condition, sensitivity and treatment goals.

Key Facts

  • Treatment time: 30–45 minutes
  • Anaesthetic: Topical numbing cream may be applied
  • Downtime: Minimal (mild swelling or redness possible)
  • Sessions: Typically 2–3 treatments recommended
  • Results: Gradual improvement over 3–8 weeks
  • Longevity: Maintenance every 6–12 months
  • Suitable for: All skin types, especially thin or damaged skin

Rejuran FAQ - Frequently Asked Questions

Where does Rejuran come from?

Rejuran is an injectable skin-healing treatment from South Korea made of polynucleotides (PN). These are highly purified DNA fragments harvested from wild salmon. Rather than filling wrinkles mechanically, it works biologically by prompting your skin cells to repair themselves.

Who is Rejuran Suitable For?

Rejuran may be suitable for individuals who:

  • Have thin or delicate skin
  • Experience under-eye crepiness or fine lines
  • Have dull or tired-looking skin
  • Want natural skin regeneration rather than filler volume
  • Have compromised or ageing skin barrier
  • Prefer subtle, progressive improvement

It may not be suitable for patients seeking immediate lifting or volumisation.

What sort of results can I expect?

Rejuran does not create immediate volumising effects. Instead, it improves skin quality progressively. Patients typically notice:

  • Smoother and softer skin texture
  • Improved hydration
  • Reduction in fine lines
  • Healthier, more resilient skin
  • Brighter and more even skin tone

Results continue to improve over several weeks as collagen production and skin repair mechanisms are activated.

How long do results last?

Results typically last 6–12 months and can be maintained with periodic treatments.

Is Rejuran a skin booster?

Yes, Rejuran can be categorised to as a skin booster, as it promotes the skin's own recovery and healing mechanisms. However, while Rejuran may be described as a skin booster, it functions differently from traditional skin boosters.

While both treatments are injected into the upper layers of the skin to improve quality rather than add volume, they use completely different active ingredients:

  • Traditional Skin Boosters are made of non-crosslinked Hyaluronic Acid (HA). They act like a micro-sponge, immediately pulling water into the skin to provide deep hydration and a temporary "glow."
  • Rejuran Skin Booster is made of Polynucleotides (PN). Instead of just adding moisture, it acts as a cellular repair treatment. It signals your skin cells to regenerate, naturally producing new collagen, healing damage, and thickening the skin barrier over time.

Is Rejuran a filler?

No. Rejuran does not add volume. It works by improving skin health, texture and elasticity through polynucleotide therapy.

Traditional fillers use hyaluronic acid to physically plump the skin and add volume to areas like the cheeks or lips. Rejuran does not change your facial structure or add volume.

Instead of masking wrinkles by filling them, Rejuran acts as a skin healer. It injects DNA building blocks that signal your skin to repair its own damaged tissue from within.

How many treatments are needed?

Most patients require a course of 2–3 treatments depending on skin condition and goals

Is there downtime after Rejuran?

Downtime is minimal, although mild swelling or small injection bumps may appear temporarily.

Is Rejuran suitable for under-eyes?

Yes. Rejuran is commonly used for delicate under-eye skin to improve crepiness, fine lines and hydration.

What aftercare is advised following Rejuran treatment?

  • Avoid strenuous exercise for 24–48 hours
  • Avoid heat exposure (saunas, steam rooms) for 48 hours
  • Avoid touching or rubbing treated areas
  • Mild swelling or bumps may occur temporarily
  • Follow personalised skincare advice provided at Clinicbe

Why Choose Clinicbe for Rejuran Injections?

At Clinicbe in Knightsbridge, Rejuran treatments are delivered within a medically-led regenerative aesthetic environment focused on precision, safety and natural outcomes.

We tailor each treatment based on skin condition, sensitivity and anatomical structure to ensure optimal distribution and effectiveness of polynucleotide therapy.

Our approach prioritises skin repair and long-term improvement rather than over-treatment, supporting healthier, stronger and more resilient skin over time.

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